| Date | Location | Result | |
| 2/23/22 | O'Connell Center (West Hartford, Conn.) | St. Joseph (Conn.) 95, Saint Joseph's (Me.) 45 | Box score |
| 2/22/22 | Wildcat Center | Saint Joseph's (Me.) 89, Johnson and Wales (RI) 81 | Box score |
| 2/19/22 | McDevitt Court | Saint Joseph's (Me.) 78, Lasell 61 | Box score |
| 2/15/22 | Mike McDevitt Court | Colby-Sawyer 94, Saint Joseph's (Me.) 83 | Box score |
| 2/12/22 | Wildcat Center | Johnson and Wales (RI) 73, Saint Joseph's (Me.) 60 | Box score |
| 2/9/22 | Paxton, MA | Anna Maria 89, Saint Joseph's (Me.) 83 | Box score |
| 02/05/22 | Northfield, VT | St. Joseph's (ME) 79, Norwich 78 | Box score |
| 2/3/22 | McDevitt Court | Saint Joseph's (Me.) 75, Emmanuel (Mass.) 73 | Box score |
| 2/1/22 | McDevitt Court | Rivier 76, Saint Joseph's (Me.) 66 | Box score |
| 01/26/22 | New London, NH | St. Joseph's (ME) 94, Colby-Sawyer 90 | Box score |
| 01/22/22 | Franklin, MA | St. Joseph's (ME) 82, Dean 73 | Box score |
| 1/20/22 | Mike McDevitt Court | St. Joseph (Conn.) 84, Saint Joseph's (Me.) 72 | Box score |
| 1/18/22 | Mike McDevitt Court | Anna Maria 84, Saint Joseph's (Me.) 75 | Box score |
| 1/15/22 | McDevitt Court | Norwich 85, Saint Joseph's (Me.) 75 | Box score |
| 1/8/22 | Boston, Mass. - Andy Yosinoff Court | Emmanuel (MA) 87, St. Joseph's (ME) 77 | Box score |
| 1/6/22 | Muldoon Center / Nashua, NH | Saint Joseph's (Me.) 76, Rivier 66 | Box score |
| 1/3/22 | McDevitt Court | Bowdoin 81, Saint Joseph's (Me.) 70 | Box score |
| 12/11/21 | Picknelly | Saint Joseph's (Me.) 78, Elms 72 | Box score |
| 12/08/21 | Weston, MA | Regis (MA) 79, St. Joseph's (ME) 73 | Box score |
| 12/4/21 | Mike McDevitt Court | Albertus Magnus 85, Saint Joseph's (Me.) 73 | Box score |
| 11/28/21 | Gorham, Maine; Hill Gym | Southern Me. 86, Saint Joseph's (Me.) 74 | Box score |
| 11/23/21 | Alfond Center | Me.-Farmington 92, Saint Joseph's (Me.) 82 | Box score |
| 11/20/21 | Bangor, Maine (Newman Gym) | Husson 84, Saint Joseph's (Me.) 69 | Box score |
| 11/18/21 | Biddeford, Maine (Harold Alfond Forum) | Univ. of New England 80, Saint Joseph's (Maine) 74 | Box score |
| 11/15/21 | Harold Alfond Center | Bates 71, Saint Joseph's (Me.) 68 | Box score |
| 11/13/21 | Worcester, MA | Saint Joseph's (Me.) 104, New England Col. 94 | Box score |
| 11/12/21 | Worcester, MA | WPI 98, Saint Joseph's (Me.) 71 | Box score |